The NO-modified HIV protease inhibitor as a valuable drug for hematological malignancies: Role of p70S6K

Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis <i>In vitro</i> and <i>In vivo</i>

Joell J. Gills, Jaclyn LoPiccolo, Junji Tsurutani et al. · Clinical Cancer Research · 2007 · 326 citations

Medicine, Oncology, Pharmacology +17

Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)

Laura R. Pearce, Gordon Alton, Daniel T. Richter et al. · Biochemical Journal · 2010 · 267 citations · Full text

Life Sciences, Cell Biology, Pharmacology +14

Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier

Ana Beloqui, Mara ngeles Solins, Alicia R. Gascn et al. · Journal of Controlled Release · 2012 · 207 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +14

Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines

William T. Couldwell, David R. Hinton, Shikun He et al. · FEBS Letters · 1994 · 192 citations

Medicine, Oncology, Pharmacology +14

HIV-1 protease inhibitor induces growth arrest and apoptosis of human multiple myeloma cells via inactivation of signal transducer and activator of transcription 3 and extracellular signal-regulated kinase 1/2

Takayuki Ikezoe, Tsuyako Saito, Kentaro Bandobashi et al. · Molecular Cancer Therapeutics · 2004 · 97 citations · Full text

Medicine, Oncology, Pharmacology +15