Biological activities of crude extracts and chemical constituents of Bael, Aegle marmelos (L.) Corr.

TLDR

Bael (Aegle marmelos) is an important medicinal plant in India, traditionally used for its astringent, antidiarrheal, antidysenteric, demulcent, antipyretic, and anti‑inflammatory properties. The review aims to examine the biological activities of isolated constituents and crude extracts of A. marmelos to identify novel therapeutic compounds. The authors review isolated chemical constituents and preclinical studies of crude extracts and pure compounds from A.

Abstract

Bael (Aegle marmelos (L.) Corr.) is an important medicinal plant of India. Leaves, fruits, stem and roots of A. marmelos have been used in ethno medicine to exploit its' medicinal properties including astringent, antidiarrheal antidysenteric, demulcent, antipyretic and anti-inflammatory activities. Compounds purified from bael have been proven to be biologically active against several major diseases including cancer, diabetes and cardiovascular diseases. Preclinical studies indicate the therapeutic potential of crude extracts of A. marmelos in the treatment of many microbial diseases, diabetes and gastric ulcer. This review covers the biological activities of some isolated chemical constituents of A. marmelos and preclinical studies on some crude extracts and pure compounds to explore novel bioactive compounds for therapeutic application.