Concepedia

QUINOLINIC ACID IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE

Gilles J. Guillemin, Kieran R. Williams, Danielle G. Smith, George A. Smythe, Juliana Croitoru‐Lamoury, Bruce J. Brew

Advances in experimental medicine and biology · 2003 · 121 citations · 35 references

DOI

Concepts

References

35

Characterization of ameboid microglia isolated from developing mammalian brain

Dana Giulian, T J Baker · Journal of Neuroscience · 1986 · 1.3K citations · Full text

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Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

Robert Schwarcz, William O. Whetsell, Richard M. Mangano · Science · 1983 · 1.3K citations

, , +16

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

Gilles J. Guillemin, Stephen J. Kerr, George A. Smythe et al. · Journal of Neurochemistry · 2001 · 535 citations · Full text

, , +15

Human macrophages convert <scp>l</scp>-tryptophan into the neurotoxin quinolinic acid

Melvyn P. Heyes, Kuniaki Saito, Sanford P. Markey · Biochemical Journal · 1992 · 448 citations · Full text

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β-Amyloid Stimulation of Inducible Nitric-oxide Synthase in Astrocytes Is Interleukin-1β- and Tumor Necrosis Factor-α (TNFα)-dependent, and Involves a TNFα Receptor-associated Factor- and NFκB-inducing Kinase-dependent Signaling Mechanism

Keith T. Akama, Linda J. Van Eldik · Journal of Biological Chemistry · 2000 · 360 citations · Full text

, , +17