The isolation and chemical properties of trichothecin, an antifungal substance from <i>Trichothecium roseum</i> Link

Abstract

Antagonism between Trichothecium roseum Link and various fungi pathogenic to plants has been reported by Whetzel (1909), Boning (1933), Koch (1934) and Greaney & Machacek (1935). Culture filtrates of T. roseum have been shown to inhibit germination of Botryti8 allii conidia (Brian & Hemming, 1947). A preliminary account of the isolation and properties of trichothecin, an antifungal compound from Trichothecium ro8eum, has been given by Freeman & Morrison (1948). The present paper gives a detailed description of the isolation and properties of the antifungal compound.