Belatacept and Sirolimus Prolong Nonhuman Primate Renal Allograft Survival Without a Requirement for Memory T Cell Depletion

The Banff 97 working classification of renal allograft pathology

Lorraine C. Racusen, Kim Solez, Robert B. Colvin et al. · Kidney International · 1999 · 3.1K citations

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B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes

Deborah J. Lenschow, Lesley Rhee, Neda Ashourian et al. · Immunity · 2000 · 2K citations · Full text

Life Sciences, Cell Biology, Immunology +16

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

Christian P. Larsen, Eric T. Elwood, Diane Z. Alexander et al. · Nature · 1996 · 1.5K citations

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A Phase III Study of Belatacept‐based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

Flavio Vincenti, B Charpentier, Yves Vanrenterghem et al. · American Journal of Transplantation · 2010 · 946 citations

Medicine, Nephrology, Pharmacology +15

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

Allan D. Kirk, David M. Harlan, Nicholas Armstrong et al. · Proceedings of the National Academy of Sciences · 1997 · 933 citations

Life Sciences, Immunology, Pharmacology +17