Age-Related Left Ventricular Changes and Their Association with Leukocyte Telomere Length in Healthy People

Abstract

Our data suggest that the ageing process leads to changes in LV structure and diastolic function and is linked with a phenotype of concentric LV remodeling. Telomere attrition is associated with age-related LV diastolic dysfunction. Telomere length appears to be a biomarker of myocardial ageing.