Adverse effects of sulfasalazine in patients with rheumatoid arthritis are associated with diplotype configuration at the N-acetyltransferase 2 gene. - Concepedia

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Adverse effects of sulfasalazine in patients with rheumatoid arthritis are associated with diplotype configuration at the N-acetyltransferase 2 gene.

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References

2002

Year

Eiichi Tanaka, Atsuo Taniguchi, Wako Urano, Hiroshi Nakajima, Yuko Matsuda, Yutaka Kitamura, Masayuki Saito, Hisashi Yamanaka, Terunobu Saito, Naoyuki Kamatani

Abstract

Genotyping the NAT2 gene followed by estimation of diplotype configuration before administration of SSZ is likely to reduce the frequency of adverse effects in Japanese patients with RA.