Journal of the Royal Society of Medicine · 1980 · 85 citations · 11 references
MedicineNuclear MedicineOncologyDiagnostic ImagingEndocrine OncologyRadionuclide TherapyEndocrine ImagingEndocrine Tumor DiagnosisEndocrine Tumor ImagingOncologic Nuclear ImagingTumor ImagingDiagnostic Radiotracer ImagingImaging Of Hormone-secreting TumorsIodine-123 ScintigraphyIodine-131 ScintigraphyRadiologic ImagingTomographyTumor Radiotracer ImagingTumor Scintigraphy
(131)Iodine ((131)I) labelled antibody directed against human chorionic gonadatrophin (hCG) was given on 21 occasions to 18 patients with hCG-producing neoplasms. Tumours were localized by external scintigraphy in 13 of 21 investigations. Positive results were obtained reliably when serum hCG exceeded 500 miu/ml and in some cases sensitivity was comparable to that of computerized tomography. A positive result probably implies viability in the tumour and this was of practical value in discriminating between necrotic deposits and living tumour before surgery.
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