Neuramin-Lactose Sulfate, a New Compound Isolated from the Mammary Gland of Rats

Abstract

Fractionationof rat mammary gland extracts by ion eschange chromatography has led to the isolation of a new low molecular weight derivative of neuraminic acid.This compound appears to be a sulfuric ester of neuramin-lactose (1) and, therefore, the name neuramin-lactose sulfate is here proposed for it.Glands obtained from the first to the sixth da.y after delivery contained an average of 3.4 mg of neuramin-lactose and 0.23 mg of neuramin-lactose sulfate per g of fresh tissue. Isolation of Neuramin-Lactose XulfcfteVol. 236, No. 9