Optics Express · 2015 · 74 citations · 44 references
EngineeringBiomedical EngineeringElectrical EngineeringOpticsPhotonicsSpectroscopyOptical DetectorsOptical ImagingOptical InstrumentationOptical SpectroscopySilicon PhotonicsTime-resolved SpectroscopyDetector Timing ResolutionDiffuse Optical ImagingDiffuse Optical SpectroscopyOptical PropertiesPhotomultiplier DetectorsSilicon PhotomultipliersTime-resolved DetectionTiming Resolution
. The detector is hosted into the probe and used in direct contact with the sample under investigation, thus providing high harvesting efficiency by exploiting the whole SiPM numerical aperture and also reducing complexity by avoiding the use of cumbersome fiber bundles. Our tests also demonstrate high accuracy and linearity in retrieving the optical properties and suitable contrast and depth sensitivity for detecting localized inhomogeneities. In addition to a strong improvement in both instrumentation cost and size with respect to legacy solutions, the setup performances are comparable to those of state-of-the-art time-domain instrumentation, thus opening a new way to compact, low-cost and high-performance time-resolved devices for diffuse optical imaging and spectroscopy.
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Diffuse optics for tissue monitoring and tomography
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