Concepedia

Enhanced Oral Bioavailability of Paclitaxel by Coadministration of the P-Glycoprotein Inhibitor KR30031

Jong Soo Woo, Chang Koo Shim, Sung‐Joo Hwang

Pharmaceutical Research · 2003 · 134 citations · 20 references

DOI

Concepts

References

20

Hypersensitivity reactions from taxol.

R B Weiss, Ross C. Donehower, Peter H. Wiernik et al. · Journal of Clinical Oncology · 1990 · 1.2K citations

, , +9

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom, Judith van Asperen, Ulrich Mayer et al. · Proceedings of the National Academy of Sciences · 1997 · 880 citations

, , +15

Clinical toxicities encountered with paclitaxel (Taxol).

Rowinsky Ek, Eisenhauer Ea, Arbuck Sg et al. · PubMed · 1993 · 698 citations

, , +12

Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients.

Robert F. Ozols, Robert E. Cunnion, R W Klecker et al. · Journal of Clinical Oncology · 1987 · 428 citations

, , +17

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine*

Chi-Yuan Wu, Leslie Z. Benet, Mary F. Hébert et al. · Clinical Pharmacology & Therapeutics · 1995 · 356 citations

, , +17