Annexin <scp>A1</scp> mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice

Abstract

Collectively, our findings reveal novel protective properties of the ANXA1 derived peptide Ac2-26 on the inflammatory and fibrotic responses induced by silica, and suggest that ANXA1 mimetic agents might be a promising strategy as innovative anti-fibrotic approaches for the treatment of silicosis.