In vitro effects of valproate and valproate metabolites on mitochondrial oxidations

Valproic acid hepatic fatalities

Fritz E. Dreifuss, Nancy Santilli, D Langer et al. · Neurology · 1987 · 485 citations

Hepatic Disorders, Hepatology, Hepatic Fatalities +14

Valproate–Induced Hepatic Injury: Analyses of 23 Fatal Cases

Hyman J. Zimmerman, Kamal G. Ishak · Hepatology · 1982 · 393 citations · Full text

The Hepatotoxicity of Valproic Acid and Its Metabolites in Rats. I. Toxicologic, Biochemical and Histopathologic Studies

J. W. Kesterson, Richard Granneman, Joseph M. Machinist · Hepatology · 1984 · 250 citations · Full text

Cytochrome P-450—Catalyzed Formation of Δ⁴-VPA, a Toxic Metabolite of Valproic Acid

Allan E. Rettie, Albert W. Rettenmeier, William N. Howald et al. · Science · 1987 · 249 citations

Reye-like syndrome associated with valproic acid therapy

R. G. Dickinson, Robert C. Harland, R K Lynn et al. · The Journal of Pediatrics · 1979 · 224 citations

Clinical Finding, Gastroenterology, Pathology +4