Concepedia

Predicting storage‐dependent damage to red blood cells using nitrite oxidation kinetics, peroxiredoxin‐2 oxidation, and hemoglobin and free heme measurements

Joo‐Yeun Oh, Ryan Stapley, Victoria M. Harper, Marisa B. Marques, Rakesh P. Patel

Transfusion · 2015 · 17 citations · 29 references

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Abstract

Measurement of Prx-2 oxidation and nitrite oxidation kinetics early during RBC storage may predict storage-dependent damage to RBC including hemolysis-dependent formation of free Hb and heme.

References

29

Nitric Oxide Scavenging by Red Blood Cell Microparticles and Cell-Free Hemoglobin as a Mechanism for the Red Cell Storage Lesion

Chenell Donadee, Nicolaas J.H. Raat, Tamir Kanias et al. · Circulation · 2011 · 552 citations · Full text

Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation

Eldad A. Hod, Ning Zhang, Set Sokol et al. · Blood · 2010 · 474 citations · Full text

Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte

Felicia M. Low, Mark B. Hampton, Alexander V. Peskin et al. · Blood · 2006 · 284 citations · Full text

Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy

Jin Hyen Baek, Felice D’Agnillo, Florence Vallelian et al. · Journal of Clinical Investigation · 2012 · 272 citations · Full text

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Evaluation of proposed FDA criteria for the evaluation of radiolabeled red cell recovery trials

Larry J. Dumont, James P. AuBuchon · Transfusion · 2008 · 256 citations