First‐in‐man safety and pharmacokinetics of synthetic ozonide <scp>OZ439</scp> demonstrates an improved exposure profile relative to other peroxide antimalarials - Concepedia

Concepedia

Publication | Open Access

First‐in‐man safety and pharmacokinetics of synthetic ozonide <scp>OZ439</scp> demonstrates an improved exposure profile relative to other peroxide antimalarials

DOI Full Paper Access

115

Citations

11

References

2012

Year

Joerg J. Moehrle, Stephan Duparc, Christoph Siethoff, Paul L. M. van Giersbergen, J. Carl Craft, Sarah Arbe‐Barnes, Susan A. Charman, María J. Gutiérrez, Sergio Wittlin, Jonathan L. Vennerstrom

British Journal of Clinical Pharmacology

Abstract

The safety and pharmacokinetic profile of OZ439 merits progression to phase 2a proof of concept studies in the target population of acute uncomplicated malaria.

References

	Year	Citations

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