Hemostatic activation during cardiopulmonary bypass with different aprotinin dosages in pediatric patients having cardiac operations

Complement and the damaging effects of cardiopulmonary bypass

James K. Kirklin · Journal of Thoracic and Cardiovascular Surgery · 1983 · 1.3K citations

Cardiogenic Shock, Cardiothoracic Surgery, Cardiac Anaesthesia +4

Complement Activation during Cardiopulmonary Bypass

Dennis E. Chenoweth, Steven W. Cooper, Tony E. Hugli et al. · New England Journal of Medicine · 1981 · 1.2K citations

Acute Lung Injury, Inflammation, Complement System +13

Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors.

Jeffrey I. Weitz, Monika Hudoba, David Massel et al. · Journal of Clinical Investigation · 1990 · 1.1K citations · Full text

EFFECT OF APROTININ ON NEED FOR BLOOD TRANSFUSION AFTER REPEAT OPEN-HEART SURGERY

David Royston, Kenneth M. Taylor, Benjamin P. Bidstrup et al. · The Lancet · 1987 · 689 citations

Cardiac Anaesthesia, Cardiothoracic Surgery, Cardiovascular Disease +7

Reduction in blood loss and blood use after cardiopulmonary bypass with high dose aprotinin (Trasylol)

Benjamin P. Bidstrup, David Royston, Ralph N. Sapsford et al. · Journal of Thoracic and Cardiovascular Surgery · 1989 · 539 citations

Cardiac Anaesthesia, Cardiovascular Disease, Medicine +10