Studies of sebum. 6. The determination of the component fatty acids of human forearm sebum by gas–liquid chromatography

A. T. James, Victor R. Wheatley

Biochemical Journal · 1956 · 112 citations · 4 references

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Abstract

c8-and tran8-diol, together with indan-2-one So far, however, there is no experimental evidence to show that epoxide formation occurs in the aniimal body during the metabolism of indene. SUMMARY 1. Indene has been administered to rabbits by stomach tube, and fractionation of ether extracts of the urine has yielded optically active c8-and tran8-indane-1:2-diol in a total amount correspond- ing to about 5 % of the dose. Acid treatment of the urine, either before or after ether extraction, yielded indan-2-one in amounts corresponding to about 25 % of the dose of indene.

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