Early ALS-type gait abnormalities in AMP-dependent protein kinase-deficient mice suggest a role for this metabolic sensor in early stages of the disease

Amyotrophic lateral sclerosis

Lokesh Wijesekera, P. Nigel Leigh · Orphanet Journal of Rare Diseases · 2009 · 948 citations · Full text

Life Sciences, Neurology, Neuroscience +14

Knockout of the α2 but Not α1 5′-AMP-activated Protein Kinase Isoform Abolishes 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranosidebut Not Contraction-induced Glucose Uptake in Skeletal Muscle

Sebastian B. Jørgensen, Benoı̂t Viollet, Fabrizio Andréelli et al. · Journal of Biological Chemistry · 2004 · 549 citations · Full text

Life Sciences, Biochemistry, Physiology +14

Dyslipidemia is a protective factor in amyotrophic lateral sclerosis

Luc Dupuis, P. Corcia, Anissa Fergani et al. · Neurology · 2008 · 545 citations

Life Sciences, Neurology, Clinical Nutrition +13

The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity

Benoı̂t Viollet, Fabrizio Andréelli, Sebastian B. Jørgensen et al. · Journal of Clinical Investigation · 2003 · 488 citations

Life Sciences, Endocrinology, Physiology +16

Amyotrophic lateral sclerosis.

PubMed · 1951 · 444 citations

Medicine, Neurology, Neurodegeneration +16