METABOLISM OF C14-LABELED GLYCINE, l-HISTIDINE, l-LEUCINE, AND l-LYSINE

Abstract

A study of the rates of incorporation in vivo of labeled amino acids into tissue proteins was undertaken to find the best time at which intermediates in the process might be found. The rates observed were so fast that we decided to investigate the process in some detail. The amino acids were L-α-aminoadipic-6-C14 acid, glycine-1-C14, L-histidine-2-C14-imidazole, L-leucine-1-C14, and L-lysine-1-C14.