The patterns of binding of RAR, RXR and TR homo‐ and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

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Medicine, Medicinal Chemistry, Pharmacology +11

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

Steven A. Kliewer, Kazuhiko Umesono, Daniel J. Noonan et al. · Nature · 1992 · 1.7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

Kazuhiko Umesono, Kevin K. Murakami, Catherine C. Thompson et al. · Cell · 1991 · 1.7K citations · Full text

Medicine, Genetics, Molecular Genetics +15

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

Steven A. Kliewer, Kazuhiko Umesono, David J. Mangelsdorf et al. · Nature · 1992 · 1.5K citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

Ben F. Luisi, Wei Xu, Zbyszek Otwinowski et al. · Nature · 1991 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +13