Concepedia

Negative transactivation of cAMP response element by familial Alzheimer's mutants of APP.

Tsuneya Ikezu, Takashi Okamoto, Katsumi Komatsuzaki, Takashi Matsui, Jeevendra Martyn, Ikuo Nishimoto

The EMBO Journal · 1996 · 38 citations · 39 references

DOIFull text

Open access

Concepts

References

39

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Alison Goate, Marie‐Christine Chartier‐Harlin, Jeremy Brown et al. · Nature · 1991 · 4.6K citations

, , +16

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Jie Kang, Hans-Georg Lemaire, Axel Unterbeck et al. · Nature · 1987 · 4.6K citations

, , +14

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

Gustavo González, Marc Montminy · Cell · 1989 · 2.5K citations

, , +14

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

, , +16

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

Roussoudan Bourtchuladze, Bruno G. Frenguelli, Julie A. Blendy et al. · Cell · 1994 · 1.8K citations

, , +16