Concepedia

Homocysteine and Cognitive Function in a Population‐Based Study of Older Adults

Jyme H. Schafer, Thomas A. Glass, Karen I. Bolla, Margaret Mintz, Anne Jedlicka, Brian S. Schwartz

Journal of the American Geriatrics Society · 2005 · 125 citations · 24 references

DOI

Abstract

Higher homocysteine levels were associated with worse function across a broad range of cognitive domains, and the magnitude of the associations was large. The data suggest that homocysteine may be a potentially important modifiable cause of cognitive dysfunction.

References

24

The CES-D Scale

Lenore Sawyer Radloff · Applied Psychological Measurement · 1977 · 52.6K citations · Full text

, , +19

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

George Davey Smith, Shah Ebrahim · International Journal of Epidemiology · 2003 · 6.2K citations

, , +21

Lowering Homocysteine in Patients With Ischemic Stroke to Prevent Recurrent Stroke, Myocardial Infarction, and Death

James F. Toole, M.R. Malinow, Lloyd E. Chambless et al. · JAMA · 2004 · 1.4K citations

Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity

Inna I. Kruman, Carsten Culmsee, Sic L. Chan et al. · Journal of Neuroscience · 2000 · 781 citations · Full text

Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study

KM Riggs, Avron Spiro, Katherine L. Tucker et al. · American Journal of Clinical Nutrition · 1996 · 519 citations · Full text

, , +10