Peripheral group I metabotropic glutamate receptors modulate nociception in mice

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

Kenneth Hargreaves, Ronald Dubner, Frederick J. Brown et al. · Pain · 1988 · 5.1K citations

Pain Medicine, Neuropathic Pain, Thermal Therapy +21

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

F. Gasparini, Kurt Lingenhöhl, Natacha Stoehr et al. · Neuropharmacology · 1999 · 720 citations

Biochemistry, Functional Selectivity, Medicine +7

The formalin test: scoring properties of the first and second phases of the pain response in rats

Frances V. Abbott, Keith B.J. Franklin, R. Frederick Westbrook · Pain · 1995 · 580 citations

Central nervous system plasticity in the tonic pain response to subcutaneous formalin injection

Terence J. Coderre, Anthony L. Vaccarino, Ronald Melzack · Brain Research · 1990 · 539 citations

Pain Syndrome, Health Sciences, Acute Pain +15

Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity

Stéphanie Puig, Linda S. Sorkin · Pain · 1996 · 471 citations