Ultrasound in Obstetrics and Gynecology · 2013 · 150 citations · 12 references
MedicineGynecologyPathologyGeneral GynecologyGynecologic UltrasoundSurgical PathologyEndometriosisGynecologic PathologyUterine ImagingUterine PathologyUterine UltrasoundAdhesionsEndometriosis DetectionEndometriosis SeverityHistological ConfirmationLikelihood RatiosRadical ResectionStaging LaparoscopyUterine Sonography
OBJECTIVE: To evaluate whether the presence of uterorectal adhesions demonstrated by transvaginal sonography (TVS) could aid as a simple sonographic predictor for deep infiltrating endometriosis (DIE) of the rectum in patients with symptoms suggestive of endometriosis. METHODS: This was a prospective multicenter study of women scheduled for laparoscopy because of symptoms suggestive of endometriosis. Patients were assessed prospectively using TVS before laparoscopy and radical resection of disease followed by histological confirmation. Sensitivity, specificity, positive (PPV) and negative (NPV) predictive values, accuracy and positive (LR+) and negative (LR-) likelihood ratios were calculated for the observation of a negative uterine 'sliding sign' on TVS in predicting the presence of DIE of the rectum. RESULTS: In total, 117 patients underwent laparoscopy and resection. Thirty-four (29%) patients had DIE of the rectum. A negative sliding sign on TVS predicted DIE of rectum with a sensitivity of 85%, specificity of 96%, PPV of 91%, NPV of 94%, accuracy of 93.1%, LR + of 23.6 and LR- of 0.15. CONCLUSIONS: Sonographic demonstration of uterorectal adhesions reflected by a negative uterine sliding sign is an easy and practical method for prediction of the presence of DIE involving the rectum. This could be a valuable 'red flag' sign for triaging patients to tertiary referral centers and specialized clinics for detailed investigation.
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Delay in the diagnosis of endometriosis: a survey of women from the USA and the UK
Ruth M. Hadfield, Helen J. Mardon, David J. Barlow et al. · Human Reproduction · 1996 · 521 citations
Medicine, Gynecology, Obstetrics +8
Diagnostic delay for endometriosis in Austria and Germany: causes and possible consequences
Gernot Hudelist, N Fritzer, A. Thomas et al. · Human Reproduction · 2012 · 474 citations
Medicine, Endocrinology, Gynecology +11