Mechanism of action of the nitrosoureas—IV

Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas.

Kurt W. Kohn · PubMed · 1977 · 292 citations

Pharmacy, Biochemistry, Molecular Biology +13

Interaction of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037) with nucleic acids and proteins in vivo and in vitro.

S Fujimura, Dezider Grünberger, I B Weinstein · PubMed · 1972 · 121 citations

Medicine, Molecular Biology, Pharmacology +7

Alkylating Activity of 1,3-Bis(2-chloroethyl)-1-nitrosourea and Related Compounds

Glynn P. Wheeler, Sue. Chumley · Journal of Medicinal Chemistry · 1967 · 78 citations

Natural Sciences, Chemistry, Pharmacology +7

Mechanism of action of 2-haloethylnitrosoureas on DNA and its relation to their antileukemic properties

J. William Lown, Larry W. McLaughlin, Yau-Min Chang · Bioorganic Chemistry · 1978 · 62 citations

Medicine, Oncology, Pharmacology +12

Reaction of 1,3-bis(2-chloroethyl)-1-nitrosourea with synthetic polynucleotides

David B. Ludlum, Barnett S. Kramer, Julie Wang et al. · Biochemistry · 1975 · 59 citations

Pharmacy, Biochemistry, Chemistry +5