Concepedia

Mechanism of action of 2-haloethylnitrosoureas on DNA and its relation to their antileukemic properties

J. William Lown, Larry W. McLaughlin, Yau-Min Chang

Bioorganic Chemistry · 1978 · 62 citations · 28 references

DOI

Concepts

References

28

Experimental evaluation of potential anticancer agents VIII. Effects of certain nitrosoureas on intracerebral L1210 leukemia.

Schabel Fm, Johnston Tp, McCALEB Gs et al. · PubMed · 1963 · 369 citations

, , +7

Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas.

Kurt W. Kohn · PubMed · 1977 · 292 citations

, , +13

Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents

J. William Lown, Soo-Khoon Sim, Rwei-Ying Chang · Biochemical and Biophysical Research Communications · 1977 · 259 citations

, , +12

The mechanism of the degradation of DNA by streptonigrin

R. Cone, S.K. Hasan, J. W. LOWN et al. · Canadian Journal of Biochemistry · 1976 · 187 citations

, , +17

The Modes of Decomposition of 1,3-Bis(2-chloroethyl)-1-nitrosourea and Related Compounds

John A. Montgomery, R Mccarthy James, G. S. MCCALEB et al. · Journal of Medicinal Chemistry · 1967 · 174 citations

, , +6