Sustained Delivery of Interleukin-2 from a Poloxamer 407 Gel Matrix Following Intraperitoneal Injection in Mice

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

Elizabeth A. Grimm, A Mazumder, H Z Zhang et al. · The Journal of Experimental Medicine · 1982 · 2.2K citations · Full text

Life Sciences, Immunology, Oncology +15

Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2.

S A Rosenberg, James J. Mulé, Paul J. Spiess et al. · The Journal of Experimental Medicine · 1985 · 741 citations · Full text

Medicine, Immunology, Oncology +13

Successful immunotherapy of murine experimental hepatic metastases with lymphokine-activated killer cells and recombinant interleukin 2.

René Lafrenière, Steven A. Rosenberg · PubMed · 1985 · 380 citations

Medicine, Immunology, Oncology +13

The fate of interleukin-2 after <i>in vivo</i> administration.

J H Donohue, S A Rosenberg · The Journal of Immunology · 1983 · 373 citations · Full text

Life Sciences, Immunology, Pharmacokinetics +12

Successful immunotherapy of natural killer-resistant established pulmonary melanoma metastases by the intravenous adoptive transfer of syngeneic lymphocytes activated in vitro by interleukin 2.

A Mazumder, S A Rosenberg · The Journal of Experimental Medicine · 1984 · 371 citations · Full text

Medicine, Immunology, Oncology +17