Novel chitosan-polycaprolactone blends as potential scaffold and carrier for corneal endothelial transplantation.

Abstract

A ratio of 75:25 (chitosan:PCL) blends showed enough mechanical properties as well as suitable support for cellular activity in cultivating BCECs. Thus, a novel methodology of biodegradable carrier from chitosan and PCL has potential to be a good replacement scaffold for raising CECs for clinical transplantation.