Concepedia

Abstract

Summary Antibodies against C57BL/6 cells were detected in serum and renal eluates of (C57BL/6 × DBA/2)F1 mice that developed nephritis after receiving injections of DBA/2 spleen cells. This model of glomerulonephritis provides an example of immune complex deposits consisting of histocompatibility antigens and antibodies against histocompatibility antigens.