Concepedia

A protein knockdown strategy to study the function of β-catenin in tumorigenesis

Feng Cong, Jianxuan Zhang, William Pao, Pengbo Zhou, Harold Varmus

BMC Molecular Biology · 2003 · 75 citations · 27 references

DOIFull text

Open access

Concepts

References

27

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations

, , +17

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

Osamu Tetsu, Frank McCormick · Nature · 1999 · 3.6K citations

, , +14

Wnt signaling and cancer

Paul Polakis · Genes & Development · 2000 · 3.2K citations · Full text

, , +17

The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway

Michael Shtutman, Jacob Zhurinsky, Inbal Simcha et al. · Proceedings of the National Academy of Sciences · 1999 · 2.2K citations · Full text

, , +12

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

Marc van de Wetering, Elena Sancho, Cornelis L. Verweij et al. · Cell · 2002 · 2K citations · Full text

, , +16