<scp>PDGF</scp> and <scp>TGF</scp>‐β promote tenascin‐<scp>C</scp> expression in subepithelial myofibroblasts and contribute to intestinal mucosal protection in mice

Abstract

The pharmacological profiles of PDGF-BB and TGF-β in colitis tissues and ISEMF suggest that increased TnC production during inflammation contributed to epithelial cell migration, remodelling and protection of intestinal barriers.