In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy

Two-Photon Laser Scanning Fluorescence Microscopy

Winfried Denk, James H. Strickler, Watt W. Webb · Science · 1990 · 9.4K citations

Natural Sciences, Biophysics, Cell Biology +17

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Peter Carmeliet, Yuval Dor, Jean-Marc Herbert et al. · Nature · 1998 · 2.5K citations

Medicine, Cancer Biology, Cell Biology +16

Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation

Gabriel Helmlinger, Fan Yuan, Marc Dellian · Nature Medicine · 1997 · 1.6K citations

Medicine, Cancer Biology, Oncology +9

Tumor Induction of VEGF Promoter Activity in Stromal Cells

Dai Fukumura, Ramnik J. Xavier, Takeyuki Sugiura et al. · Cell · 1998 · 979 citations · Full text

Medicine, Cancer Biology, Cell Biology +16

Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex

David Kleinfeld, Partha P. Mitra, Fritjof Helmchen et al. · Proceedings of the National Academy of Sciences · 1998 · 837 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17