Sweet and bitter diterpene-glucosides from leaves of Rubus suavissimus.

Abstract

From leaves of Rubus suavissimus, two minor ent-kaurane type diterpene glucosides were isolated in addition to the major sweet principle, rubusoside (1). Of these glucosides, the bitter glycoside (2) was identified as sugeroside which has been isolated from leaes of Ilex sugerokii var. Brevipedunculata etc. The new glucoside (3) named suavioside-A tastes sweet and the structure was elucidated as 17-O-β-D-glucoside of ent-kaurane-3α, 16β, 17-triol.