Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice

International Trial of the Edmonton Protocol for Islet Transplantation

A. M. James Shapiro, Camillo Ricordi, Bernhard J. Hering et al. · New England Journal of Medicine · 2006 · 1.9K citations · Full text

Medicine, Endocrinology, Surgery +16

Suppressor of Cytokine Signaling 1 (SOCS-1) and SOCS-3 Cause Insulin Resistance through Inhibition of Tyrosine Phosphorylation of Insulin Receptor Substrate Proteins by Discrete Mechanisms

Kohjiro Ueki, Tatsuya Kondo, C. Ronald Kahn · Molecular and Cellular Biology · 2004 · 678 citations · Full text

Life Sciences, Endocrinology, Immunology +17

Target cell defense prevents the development of diabetes after viral infection

Malin Flodström‐Tullberg, Amy Maday, Deepika Balakrishna et al. · Nature Immunology · 2002 · 216 citations

Life Sciences, Cell Biology, Immunology +14

Neurogenin3 Is Sufficient for Transdetermination of Hepatic Progenitor Cells into Neo-Islets In Vivo but Not Transdifferentiation of Hepatocytes

Vijay Yechoor, Victoria Liu, Christie Espiritu et al. · Developmental Cell · 2009 · 179 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

A High-Efficiency Cre/loxP-Based System for Construction of Adenoviral Vectors

Robin J. Parks, Derek T. Cummings, Carole Evelegh et al. · Human Gene Therapy · 1999 · 109 citations

Life Sciences, Biotechnology, Molecular Biology +13