Journal of Bacteriology · 1982 · 35 citations · 15 references
Life SciencesBiochemistryBiologyCellular MetabolismLipid BiochemistryMorphogenesisFatty Acid MetabolismFungal DevelopmentLipid BiosynthesisLipid Biosynthesis InhibitionLipid MetabolismPhospholipid MetabolismCell Growth RegulationCeramide BiosynthesisDecarboxylase EnzymesMembrane Lipid Biosynthesis InhibitionPhospholipid Turnover
Lipid synthesis increases coordinately with protein and RNA synthesis during morphogenesis of Mucor racemosus. The lipid synthesis inhibitor cerulenin can completely block morphogenesis under conditions in which cell growth continues. An increase in phospholipid turnover may be an important correlate to morphogenesis of Mucor spp., especially the turnover of phosphotidyl inositol and phosphatidyl ethanolamine. The increase in ornithine decarboxylase, which occurs during morphogenesis, is inhibited by the addition of cerulenin.
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Thomas M. McIntyre, B K Chamberlain, Robert E. Webster et al. · Journal of Biological Chemistry · 1977 · 54 citations · Full text