Usefulness of liquid-based cytology specimens for the immunocytochemical study of p16 expression and human papillomavirus testing

Abstract

The results of the current study confirmed that the immunohistochemical detection of p16 was more sensitive and specific than HPV status in cervical lesions using a liquid-based method as well as tissue samples, suggesting that p16 should be used as a satisfactory biomarker for the primary screening of cervical cytology.