Serum-Induced Keratinization Processes in an Immortalized Human Meibomian Gland Epithelial Cell Line

Abstract

Serum treatment of HMGEC caused lipid droplet formation to some extent but also induced keratinization. The cells did not produce typical meibum lipids under these growth conditions. HMGEC are well suited to study (hyper)keratinization processes of meibomian gland epithelial cells in vitro.