Stimulation of host defense against experimental cancer. I. Zymosan and sarcoma 180 in mice.

Abstract

Summary 1.Treatment of mice bearing Sarcoma 180 with small doses of the yeast product zymosan has been shown to promote a significant degree of tumor loss. 2.The results of various experiments indicate that this phenomenon is entirely an immune reaction mediated by the host. 3.Involvement of some function of the properdin system is suggested by correlative evidence, but remains to be proved or disproved by more direct means.