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Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers.

ChromatinNucleic Acid ChemistryChromatin StructureChromatin RemodelingMedicineNatural SciencesNucleic Acid BiochemistryOligonucleotideMolecular BiologyNuclear OrganizationEukaryotic TopoisomerasesNucleic Acid TopologyDna CrossoversStructural BiologyBiomolecular Engineering