Aldosterone-Induced Inflammation in the Rat Heart

The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

Bertram Pitt, Faı̈ez Zannad, Willem J. Remme et al. · New England Journal of Medicine · 1999 · 9.1K citations · Full text

Medicine, Cardiology, Pharmacology +16

The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

Bertram Pitt, Faı̈ez Zannad, Willem J. Remme et al. · Survey of Anesthesiology · 2000 · 2.9K citations

Medicine, Cardiology, Pharmacology +16

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

Sanjay Rajagopalan, Stephan Kurz, Thomas Münzel et al. · Journal of Clinical Investigation · 1996 · 2.4K citations · Full text

Life Sciences, Pharmacology, Physiology +16

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

Ryszard J. Gryglewski, Richard Palmer, Salvador Moncada · Nature · 1986 · 2.4K citations

Life Sciences, Cell Biology, Physiology +13

Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD).

Gary S. Francis, Claude R. Benedict, David E. Johnstone et al. · Circulation · 1990 · 1.4K citations

Medicine, Cardiology, Physiology +10