The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

Jimmy K. Eng, Ashley L. McCormack, John R. Yates · Journal of the American Society for Mass Spectrometry · 1994 · 6.6K citations

Life Sciences, Biochemistry, Bioinformatics +17

Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes

Dayle A. Hager, Richard R. Burgess · Analytical Biochemistry · 1980 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +13

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

Takuro Wada, Toshiyuki Takagi, Yuki Yamaguchi et al. · Genes & Development · 1998 · 747 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

FACT, a Factor that Facilitates Transcript Elongation through Nucleosomes

George M. Orphanides, Gary LeRoy, Chun-Hsiang Chang et al. · Cell · 1998 · 659 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

Grant A. Hartzog, Takuro Wada, Hiroshi Handa et al. · Genes & Development · 1998 · 462 citations · Full text

Life Sciences, Genetics, Molecular Biology +17