Inactivation of protein tyrosine phosphatases by dietary isothiocyanates

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

Lindsey J. Macpherson, Adrienne E. Dubin, Michael J. Evans et al. · Nature · 2007 · 1.1K citations · Full text

Molecular Pharmacology, Signal Transduction, Molecular Physiology +14

TRP channel activation by reversible covalent modification

A. Scott Hinman, Huai-hu Chuang, Diana M. Bautista et al. · Proceedings of the National Academy of Sciences · 2006 · 877 citations · Full text

Pungent Principle, Signal Recognition, Molecular Biology +17

Identification of Sensor Cysteines in Human Keap1 Modified by the Cancer Chemopreventive Agent Sulforaphane

Fei Hong, Michael L. Freeman, D.C. Liebler · Chemical Research in Toxicology · 2005 · 397 citations

Recent Advances in the Discovery of Competitive Protein Tyrosine Phosphatase 1B Inhibitors for the Treatment of Diabetes, Obesity, and Cancer

Andrew P. Combs · Journal of Medicinal Chemistry · 2009 · 314 citations · Full text

Drug Target, Altmetric Attention Score, Chemical Biology +16

Antibacterial Mechanism of Allyl Isothiocyanate

Chia‐Min Lin, James F. Preston, Cheng–I Wei · Journal of Food Protection · 2000 · 294 citations

Bioorganic Chemistry, Allyl Isothiocyanate, Antibacterial Agent +3