The Effects of Exenatide Microsphere on Serum <scp>BGP</scp> and <scp>ALP</scp> Levels in <scp>ZDF</scp> Rats after Implantation

Abstract

The present results suggest that injection of delayed release microsphere of exenatide on ZDF rats can release exenatide at a steady rate and the blood glucose can be controlled at a constant level. Implant survival rates could be enhanced in DM subjects when blood plasma glucose level is under control; the serum levels of BGP in this study seems to have no relationship with local osseointegration, whereas the serum levels of ALP might offer insights into the activity of osseointegration around the implant surface.