Organocatalytic Synthesis of (Arylselanyl)phenyl‐1<i>H</i>‐1,2,3‐triazole‐4‐carboxamides by Cycloaddition between Azidophenyl Arylselenides and β‐Oxo‐amides

Abstract

Abstract We describe the use of β‐oxo‐amides in organocatalytic cycloaddition with aryl azidophenyl selenides. The cycloaddition reactions were performed under mild conditions, with β‐oxo‐amides and aryl azidophenyl selenides in the presence of a catalytic amount of Et 2 NH (5 mol‐%), and the corresponding products were obtained in good to excellent yields. This organocatalytic methodology tolerated a range of substituents either in the β‐oxo‐amides or in the aryl azidophenyl selenides and proved to be an efficient methodology for the combinatorial synthesis of new selenium‐containing triazole compounds.