A STUDY OF THE CHANGES IN SERUM CHOLESTEROL, GASTRIC SECRETION AND CARBOHYDRATE METABOLISM IN PATIENTS WITH TOXIC GOITER

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Article1 July 1938A STUDY OF THE CHANGES IN SERUM CHOLESTEROL, GASTRIC SECRETION AND CARBOHYDRATE METABOLISM IN PATIENTS WITH TOXIC GOITERJAMES S. MCELROY, M.D., EDITH B. SCHUMAN, M.D., JAMES O. RITCHEY, M.D., F.A.C.P.JAMES S. MCELROY, M.D.Search for more papers by this author, EDITH B. SCHUMAN, M.D.Search for more papers by this author, JAMES O. RITCHEY, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-1-106 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1922, Epstein and Lande1studied the blood cholesterol of 24 patients, 14 of whom had exophthalmic goiter and 10 of whom had toxic nodular goiter. The conclusion from this group was that, in general, the decrease in blood cholesterol bears a direct relationship to the extent of increase of the basal metabolic rate. In nine of the 14 cases this was true. The lowest basal metabolic rate of plus 14 corresponded to a blood cholesterol of 196 mg. per 100 c.c., and the highest basal rate of plus 82 to a cholesterol of 90 mg. However, in this group...Bibliography1. EPSTEINLANDE AAH: Studies on blood lipoids; the relationship of cholesterol and protein deficiency to basal metabolism, Arch. Int. Med., 1922, xxx, 563-577. CrossrefGoogle Scholar2. GARDNERGAINSBOROUGH JAH: The relationship of plasma cholesterol and basal metabolism, Brit. Med. Jr., 1928, ii, 935-937. CrossrefGoogle Scholar3. MASONHUNTHURXTHAL RLHMLM: Blood cholesterol values in hyperthyroidism and hypothyroidism—their significance, New England Jr. Med., 1930, cciii, 1273-1278. CrossrefGoogle Scholar4. HURXTHAL LM: Blood cholesterol in thyroid disease; analysis of findings in toxic and non-toxic goitres before treatment, Arch. Int. Med., 1932, li, 22-32. Google Scholar5. HURXTHAL LM: Blood cholesterol in thyroid disease; effect of treatment, Arch. Int. Med., 1933, lii, 86-95. CrossrefGoogle Scholar6. FORBESIRVING JC: The determination of cholesterol in whole blood, Jr. Lab. and Clin. Med., 1930, xvi, 909-912. Google Scholar7. LERMANPIERCEBROGAN JFDAJ: Gastric acidity in normal individuals, Jr. Clin. Invest., 1932, xi, 155-165. CrossrefGoogle Scholar8. LERMANMEANS JJH: Gastric secretion in exophthalmic goitre and myxedema, Jr. Clin. Invest., 1932, xi, 167-182. CrossrefGoogle Scholar9. WILKINSON SA: Gastric acidity in thyroid dysfunction, Jr. Am. Med. Assoc., 1922, ci, 2,097-2,099. Google Scholar10. GEYELIN HR: The carbohydrate metabolism in hyperthyroidism as determined by examination of blood and urine, Arch. Int. Med., 1915, xvi, 975-988. CrossrefGoogle Scholar11. JOHN HJ: Carbohydrate metabolism in hyperthyroidism, Endocrinology, 1917, xi, 497-578. Google Scholar12. JOHN HJ: A study of 1,100 glucose tolerance tests, Med. Jr. and Rec., 1930, cxxxi, 287. Google Scholar13. GARDNER-HILLBRETTSMITH BHPCJF: Carbohydrate metabolism in myxedema, Quart. Jr. Med., 1925, xviii, 327-334. CrossrefGoogle Scholar14. WILDERSANSUM RMWD: Glucose tolerance in health and disease, Arch. Int. Med., 1917, ixx, 310-334. Google Scholar15. EXTONROSE WGAR: The one hour two-dose dextrose tolerance test, Am. Jr. Clin. Path., 1934, iv, 381-399. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, Indiana*Received for publication July 29, 1937.From the Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPhysiological Effects of the Thyroid HormonesBibliographyPreoperative and postoperative treatment of the toxic thyroidDer Verlauf der Alimentären Hyperlipämie bei Behandeltem Und Unbehandeltem Hypo- und HyperthyreoidismusGastric anacidity: Its physiologic and clinical significance and its managementOn the Cholesterol Content of the Blood Serum in Thyrotoxicosis 1 July 1938Volume 12, Issue 1Page: 106-114KeywordsBloodCarbohydrate metabolismCholesterol ePublished: 1 December 2008 Issue Published: 1 July 1938 PDF downloadLoading ...