Glutathione, glutathione‐dependent enzymes and antioxidant status in erythrocytes from children treated with high‐dose paracetamol

Abstract

In febrile children, treatment with repeated supratherapeutic doses of paracetamol is associated with reduced antioxidant status and erythrocyte glutathione concentrations. These significant changes may indicate an increased risk for hepatotoxicity and liver damage.