Concepedia

Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study

Xin Yang, Kai Zheng, Ke Lin, Guifeng Zheng, Hai Zou, Jian Min Wang

PLoS ONE · 2015 · 106 citations · 25 references

DOIFull text

Open access

Abstract

It was found that enhanced anaerobic catabolism and reduced aerobic oxidation regulated by HIF pathway are newly recognized factors contributing to the progression of RA, and low glucose and high lactic acid concentration in synovial fluid may be the potential biomarker of RA.

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Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum

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