Glomerulosclerosis and body growth are mediated by different portions of bovine growth hormone. Studies in transgenic mice. - Concepedia

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Glomerulosclerosis and body growth are mediated by different portions of bovine growth hormone. Studies in transgenic mice.

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References

1993

Year

Chih‐Wei Yang, Liliane J. Striker, Carlo Pesce, W Y Chen, E P Peten, Sandra Elliot, Toshiya Doi, John J. Kopchick

Abstract

These data indicated that development of glomerulosclerosis and body growth promotion were mediated by different regions of the growth hormone molecule. The glomerular response to bGH was unique and consisted of increased size and glomerulosclerosis.