Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

James E. Strong · The EMBO Journal · 1998 · 558 citations

Life Sciences, Molecular Biology, Oncology +14

Replication of ONYX-015, a Potential Anticancer Adenovirus, Is Independent of p53 Status in Tumor Cells

Thomas Rothmann, Arnd Hengstermann, Noel J. Whitaker et al. · Journal of Virology · 1998 · 354 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Studies on the use of viruses in the treatment of carcinoma of the cervix

Robert R. Smith, Robert J. Huebner, Wallace P. Rowe et al. · Cancer · 1956 · 329 citations · Full text

Medicine, Gynecology, Oncology +10

Interferon-resistant Human Melanoma Cells Are Deficient in ISGF3 Components, STAT1, STAT2, and p48-ISGF3γ

Lee H. Wong, Kenia G. Krauer, Irene Hatzinisiriou et al. · Journal of Biological Chemistry · 1997 · 236 citations · Full text

Life Sciences, Immunology, Molecular Biology +13

The Herpes Simplex Virus US11 Protein Effectively Compensates for the γ134.5 Gene if Present before Activation of Protein Kinase R by Precluding Its Phosphorylation and That of the α Subunit of Eukaryotic Translation Initiation Factor 2

Kevin A. Cassady, Martin Gross, Bernard Roizman · Journal of Virology · 1998 · 188 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17