Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine.

Abstract

4-Formylaminoantipyrine, a new metabolite of aminopyrine, was formed on the incubation with rat or rabbit liver slices, or with the microsomal fraction of rabbit liver.